Look-alike sound-alike (LASA) drugs are medications that have similar names, spelling, or packaging, increasing the risk of confusion and medication errors. This can happen between different medications, brand-name and generic versions, or generic-generic versions.

Insulin and Isoprinosine. Adrenaline and Atropine.

In high-pressure healthcare settings, sound-alike, look-alike medications (LASAs) are not just a nuisance—they’re a quiet threat to patient safety.

Despite best intentions, medication mix-ups continue to harm patients globally, often with devastating consequences. According to the WHO, medication errors account for over a million preventable deaths and injuries annually, and LASA confusion remains a key contributor.

Why do these errors persist?

Because urgency often outruns caution:

A quick grab from a similar-looking vial during a code blue.

A name misheard in a noisy ward.

Medications stored alphabetically, side-by-side, with nearly identical packaging.

In the moment, these split-second decisions can cost lives.

What can we do?

📌 A label alone isn’t enough. We need a multi-layered defense against these errors.

✔ Storage strategies: Separate look-alike/sound-alike medications, especially high-alert drugs.

✔ Labeling techniques: Use Tall-Man lettering (e.g., DOBUTamine vs. DOPamine) and bold warnings.

✔ Barcode scanning and verification: Make double-checks the norm, not the exception.

✔ Staff education: Ongoing training to reinforce awareness of LASAs.

✔ Reporting culture: Near-misses should be reported and reviewed—not punished.

It’s time we stop treating LASA issues as inevitable and start addressing them as predictable and preventable system failures.

Let’s ask ourselves:

Is my facility actively identifying and managing LASA risks?

Are we focusing not just on individual vigilance, but on system-level safeguards?

Source: https://www.who.int/initiatives/medication-without-harm/?utm